Louis Robert Desfosses Jr., 56 years of age, passed away on Saturday September 14, 2019, at Strong Memorial Hospital's Palliative Care and Hospice Unit. Louis was born January 26, 1963 in Massachusetts to the late Dr. Louis and Judith Desfosses Sr. He is predeceased by sister Julie Desfosses. He is survived by his wife Cindy Ammer Desfosses, sister Suzanne Desfosses-Gilliam (Aaron), Aaron (Taylor) Gilliam, Samantha Gilliam and Corey Bektas, In laws, Josephine Wilfeard, Mark and John (Justin) Ammer, Susan (Frank/Michael) Polimeni and many Aunts and Uncles, Cousins, Nieces, Nephews and Friends. Lou loved biking, running, walking his dog Sally, and fundraising for his favorite causes Tour de Cure, Annual Step it Up for Pancreatic Cancer 5k, and Thrive to Survive through his own charitable Notorious Lou Foundation. Friends and Family are invited to call Wednesday September 18, between the hours of 5 to 6 PM at Fowler Funeral Home 340 West Avenue Brockport NY 14420. A memorial service will take place at 6:00 pm. In lieu of flowers, memorial donations may be made to the Wilmot Cancer Institute 601 Elmwood Ave Rochester NY 14642.